It's possible, but not likely, as this is a microbiome rejuvenation program, not targeted at the kidneys or gallbladder. However, many times the galbladder is significantly relieved during the purge and many have released and seen stones. Our advice to support the kidneys: increase your lemon water intake up to a full 2 liters daily and adding in 1 cup of chopped parsley daily. Also, you can purchase rosehips from the health food store to help with your kidney balancing as well and follow the dose on the bottle. One last thing is that bioflavinoids, the antioxidant in the rind of citrus is highly supportive to the kidneys so you could wash and freeze and organic lemon and then shred the entire thing in a food processor and use 2 T a day in your water (and eat/chew the rind).