Yes, after running a 30-day clinical trial with 38 relapsed SIBO Gut Thrivers in April 2015, we’ve worked on addressing the brain-gut axis throughout their program. We’ve done so by incorporating yogic breathing, gargling, extending their path purge, and developing a new strategy for reseeding. In addition, we’re using salt flushes to empty their intestines from top to bottom, while also closing the ileocecal valve. Our trial used two key neurological supplements in heavy doses which will be available to the Plan S crowd still struggling with slow motility toward the end of the program. The whole thrust of this program is to change the terrain. The Pathogen Purge "knocks down" the offenders. The Recolonization brings in "peace-keepers", lowers inflammation, repairs leaky gut, improves motility, and allows the human immune system to reestablish indigenous and genetically-supportive colonies. When the brain senses the proper input (i.e. - less inflammation, improved diet, consistent lactobacillus, energized enterocyte cells), then the "bidirectional" communications support proper motility and inhibit return of SIBO. This is a master strategy which is working wonders to prevent relapse— as long as you listen to your own body about when it’s time to introduce probiotics and how you introduce them (hence why this group introduces them only via enema and not orally at first).